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Case study 10 / 12 · Division I
Division I · Case Study 10

Pharmaceuticals

Advanced Oxidation + MBR + GAC/RO

Pharmaceutical and fine-chemical manufacturing produces complex, batch-variable effluents — high and fluctuating COD, residual actives and antibiotics that inhibit biology, spent solvents, high TDS and swinging pH.

>95%
COD removal
>90%
API breakdown
Reuse
MBR permeate
Selected treatment train
Segregated → Equalisation + pH → Advanced oxidation → Anaerobic → MBR (aerobic) → GAC / RO polish → Reuse
Indicative influent characteristics
COD mg/L 2,000–30,000
BOD₅:COD – 0.1–0.4
APIs mg/L 1–500
TDS mg/L 2,000–20,000
Total N mg/L 50–1,200
pH – 2–11
Typical performance
removal (%)
95%
COD
90%
API
85%
Total N
92%
Reuse
Why this configuration
Advanced oxidation breaks refractory and antibiotic compounds that inhibit biology.
MBR retains slow-growing biomass and delivers a solids-free permeate.
GAC / RO polishing captures trace active ingredients to micro-pollutant limits.
Buffering & segregation tame the wide swings in load, pH and toxicity.
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